Non-pharmacological interventions in hypertension: A community-based cross-over randomized controlled trial

Non-pharmacological interventions in hypertension: A community-based cross-over randomized controlled trial

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Background: Hypertension is the most prevalent non-communicable disease causing significant morbidity/mortality through cardiovascular, cerebrovascular, and renal complications.Objectives: This community-based study tested the efficacy of non-pharmacological interventions in preventing/controlling hypertension.Materials and Methods: This is a cross-over Board Game randomized controlled trial (RCT) of the earlier RCT (2007) of non-pharmacological interventions in hypertension, conducted in the urban service area of our Institute.The subjects, prehypertensive and hypertensive young adults (98 subjects: 25, 23, 25, 25 in four groups) were randomly allotted into a group that he/she had not belonged to in the earlier RCT: Control (New Group I), Physical Exercise (NG II)-brisk walking for 50 to 60 minutes, three to four days/week, Salt Intake Reduction (NG III) to at least half of their previous intake, Yoga (NG IV) for 30 to 45 minutes/day, five days/week.Blood pressure was measured before and after eight weeks of intervention.

Analysis was by ANOVA with a Games-Howell post hoc test.Results: Ninety-four participants (25, 23, 21, 25) completed the study.All three intervention groups showed significant reduction in BP (SBP/DBP mmHg: 5.3/6.0 in NG II, 2.

5/2.0 in NG III, and 2.3/2.4 in NG IV, respectively), while the Control Group showed no significant difference.Persistence of significant reduction in BP in the three intervention groups after cross-over confirmed the biological plausibility of Ground Effects Kit these non-pharmacological interventions.

This study reconfirmed that physical exercise was more effective than Salt Reduction or Yoga.Salt Reduction, and Yoga were equally effective.Conclusion: Physical exercise, salt intake reduction, and yoga are effective non-pharmacological methods for reducing blood pressure in young pre-hypertensive and hypertensive adults.